There are a few different ways you offer wholesale prices for your shop:
1. Set up discount codes
One way to offer wholesale pricing is through the use of discount codes.
2. Use an app
With the help of a wholesale app you can offer wholesale prices that are kept separate from retail prices.
3. Open a separate wholesale store
You can open a second store for wholesale purposes at www.shopify.com. If you'd like to transfer any or all of the content from an existing store to your new one, you can read here about how to duplicate, backup, or transfer your store.
4. Customize your store to restrict access
Shopify themes can be customized to restrict access based on customer accounts.